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REFERENCES

1. Krug, A., Towarowski, A., Britsch, S., Rothenfusser, S., Hornung, V., Bals, R., Giese, T., Engelmann, H., Endres, S., Krieg, A. M. and Hartmann, G.,  Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12 ,  Eur J Immunol  31,  3026-37, 2001. 
2. Autschbach, F., Giese, T., Gassler, N., Sido, B., Heuschen, G., Heuschen, U., Zuna, I., Schulz, P., Weckauf, H., Berger, I., Otto, H. F. and Meuer, S. C.,  Cytokine/chemokine messenger-RNA expression profiles in ulcerative colitis and Crohn´s disease ,  Virchows Arch  441,  500-13, 2002. 
3. Birkenkamp-Demtroder, K., Christensen, L. L., Olesen, S. H., Frederiksen, C. M., Laiho, P., Aaltonen, L. A., Laurberg, S., Sorensen, F. B., Hagemann, R. and TF, O. R.,  Gene expression in colorectal cancer,  Cancer Res  62,  4352-63, 2002. 
4. Hornung, V., Rothenfusser, S., Britsch, S., Krug, A., Jahrsdorfer, B., Giese, T., Endres, S. and Hartmann, G.,  Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides,  J Immunol  168,  4531-7, 2002. 
5. Kraynack, N. C., Corey, D. A., Elmer, H. L. and Kelley, T. J.,  Mechanisms of NOS2 regulation by Rho GTPase signaling in airway epithelial cells,  Am J Physiol Lung Cell Mol Physiol  283,  L604-11, 2002. 
6. Reddy, V. A., Iwama, A., Iotzova, G., Schulz, M., Elsasser, A., Vangala, R. K., Tenen, D. G., Hiddemann, W. and Behre, G.,  Granulocyte inducer C/EBPalpha inactivates the myeloid master regulator PU.1: possible role in lineage commitment decisions,  Blood  100,  483-90, 2002. 
7. C Y Cheung, L L M Poon, A S Lau, W Luk, Y L Lau, K F Shortridge, S Gordon, Y Guan, J S M Peiris,  Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?,  THE LANCET  360,  1831-1837, 2002. 
8. Giese, N. A., Raykov, Z., DeMartino, L., Vecchi, A., Sozzani, S., Dinsart, C., Cornelis, J. J. and Rommelaere, J.,  Suppression of metastatic hemangiosarcoma by a parvovirus MVMp vector transducing the IP-10 chemokine into immunocompetent mice,  Cancer Gene Ther  9,  432-42, 2002. 
9. Backhed, F., Torstensson, E., Seguin, D., Richter-Dahlfors, A. and Rokbi, B.,  Helicobacter pylori infection induces interleukin-8 receptor expression in the human gastric epithelium,  Infect Immun  71,  3357-60, 2003. 
10. Giese, T., Zimmermann, K. and Meuer, S. C.,  Functional characterization of pro-biotic pharmaceuticals by quantitative analysis of gene expression,  Arzneimittelforschung  53,  385-91, 2003. 
11. Ghoreschi, K., Thomas, P., Breit, S., Dugas, M., Mailhammer, R., van Eden, W., van der Zee, R., Biedermann, T., Prinz, J., Mack, M., Mrowietz, U., Christophers, E., Schlondorff, D., Plewig, G., Sander, C. A. and Rocken, M.,  Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease,  Nat Med  9,  40-6, 2003. 
12. Hartmann, E., Wollenberg, B., Rothenfusser, S., Wagner, M., Wellisch, D., Mack, B., Giese, T., Gires, O., Endres, S. and Hartmann, G.,  Identification and functional analysis of tumor-infiltrating plasmacytoid dendritic cells in head and neck cancer,  Cancer Res  63,  6478-87, 2003. 
13. Kerkmann, M., Rothenfusser, S., Hornung, V., Towarowski, A., Wagner, M., Sarris, A., Giese, T., Endres, S. and Hartmann, G.,  Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells,  J Immunol  170,  4465-74, 2003. 
14. Kreiselmeier, N. E., Kraynack, N. C., Corey, D. A. and Kelley, T. J.,  Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells,  Am J Physiol Lung Cell Mol Physiol  285,  L1286-95, 2003. 
15. Krug, A., Rothenfusser, S., Selinger, S., Bock, C., Kerkmann, M., Battiany, J., Sarris, A., Giese, T., Speiser, D., Endres, S. and Hartmann, G.,  CpG-A oligonucleotides induce a monocyte-derived dendritic cell-like phenotype that preferentially activates CD8 T cells,  J Immunol  170,  3468-77, 2003. 
16. Schuster, C., Forster, K., Dierks, H., Elsasser, A., Behre, G., Simon, N., Danhauser-Riedl, S., Hallek, M. and Warmuth, M.,  The effects of Bcr-Abl on C/EBP transcription-factor regulation and neutrophilic differentiation are reversed by the Abl kinase inhibitor imatinib mesylate,  Blood 101  101,  655-63, 2003. 
17. Eibert, S. M., Lee, K. H., Pipkorn, R., Sester, U., Wabnitz, G. H., Giese, T., Meuer, S. C. and Samstag, Y.,  Cofilin peptide homologs interfere with immunological synapse formation and T cell activation,  Proc Natl Acad Sci U S A  101,  1957-62, 2004. 
18. Eisold, S., Ryschich, E., Linnebacher, M., Giese, T., Nauheimer, D., Wild, A., Bartsch, D. K., Buchler, M. W. and Schmidt, J.,  Characterization of FAMPAC, a newly identified human pancreatic carcinoma cell line with a hereditary background,  Cancer  100,  1978-86, 2004. 
19. George, S., Ruan, X. Z., Navarrete, C., Turner, D., Reynard, M., Sweny, P., Hamilton, G., Wheeler, D. C., Powis, S. H., Moorhead, J. F. and Varghese, Z.,  Renovascular disease is associated with low producer genotypes of the anti-inflammatory cytokine interleukin-10,  Tissue Antigens  63,  470-5, 2004. 
20. Giese, T., Zeier, M., Schemmer, P., Uhl, W., Schoels, M., Dengler, T., Buechler, M. and Meuer, S.,  Monitoring of NFAT-regulated gene expression in the peripheral blood of allograft recipients: a novel perspective toward individually optimized drug doses of cyclosporine A,  Transplantation  77,  339-44, 2004. 
21. Goutagny, N., Vieux, C., Decullier, E., Ligeoix, B., Epstein, A., Trepo, C., Couzigou, P., Inchauspe, G. and Bain, C.,  Quantification and functional analysis of plasmacytoid dendritic cells in patients with chronic hepatitis C virus infection,  J Infect Dis  189,  1646-55, 2004. 
22. Guo, J., Kleeff, J., Li, J., Ding, J., Hammer, J., Zhao, Y., Giese, T., Korc, M., Buchler, M. W. and Friess, H.,  Expression and functional significance of CDC25B in human pancreatic ductal adenocarcinoma,  Oncogene  23,  71-81, 2004. 
23. Guweidhi, A., Kleeff, J., Giese, N., El Fitori, J., Ketterer, K., Giese, T., Buchler, M. W., Korc, M. and Friess, H.,  Enhanced expression of 14-3-3sigma in pancreatic cancer and its role in cell cycle regulation and apoptosis,  Carcinogenesis  2004. 
24. Kayed, H., Kleeff, J., Keleg, S., Guo, J., Ketterer, K., Berberat, P. O., Giese, N., Esposito, I., Giese, T., Buchler, M. W. and Friess, H.,  Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer,  Int J Cancer  110,  668-76, 2004. 
25. Kraus, A. A., Raftery, M. J., Giese, T., Ulrich, R., Zawatzky, R., Hippenstiel, S., Suttorp, N., Kruger, D. H. and Schonrich, G.,  Differential antiviral response of endothelial cells after infection with pathogenic and nonpathogenic hantaviruses,  J Virol  78,  6143-50, 2004. 
26. Li, J., Kleeff, J., Guweidhi, A., Esposito, I., Berberat, P. O., Giese, T., Buchler, M. W. and Friess, H.,  RUNX3 expression in primary and metastatic pancreatic cancer,  J Clin Pathol  57,  294-9, 2004. 
27. Muller, D. B., Raftery, M. J., Kather, A., Giese, T. and Schonrich, G.,  Frontline: Induction of apoptosis and modulation of c-FLIPL and p53 in immature dendritic cells infected with herpes simplex virus,  Eur J Immunol  34,  941-51, 2004. 
28. Poeck, H., Wagner, M., Battiany, J., Rothenfusser, S., Wellisch, D., Hornung, V., Jahrsdorfer, B., Giese, T., Endres, S. and Hartmann, G.,  Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of T-cell help,  Blood  103,  3058-64, 2004. 
29. Stallmach, A., Giese, T., Schmidt, C., Meuer, S. C. and Zeuzem, S. S.,  Severe anaphylactic reaction to infliximab: successful treatment with adalimumab - report of a case,  Eur J Gastroenterol Hepatol  16,  627-30, 2004. 
30. Stallmach, A., Giese, T., Schmidt, C., Ludwig, B., Mueller-Molaian, I. and Meuer, S. C.,  Cytokine/chemokine transcript profiles reflect mucosal inflammation in Crohn´s disease,  Int J Colorectal Dis  19,  308-15, 2004. 
31. Thurfjell, N., Coates, P. J., Uusitalo, T., Mahani, D., Dabelsteen, E., Dahlqvist, A., Sjostrom, B., Roos, G. and Nylander, K.,  Complex p63 mRNA isoform expression patterns in squamous cell carcinoma of the head and neck,  Int J Oncol  25,  27-35, 2004. 
32. Wagner, M., Poeck, H., Jahrsdoerfer, B., Rothenfusser, S., Prell, D., Bohle, B., Tuma, E., Giese, T., Ellwart, J. W., Endres, S. and Hartmann, G.,  IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA,  J Immunol  172,  954-63, 2004. 
33. Dummer, R., Hassel, J. C., Fellenberg, F., Eichmueller, S., Maier, T., Slos, P., Acres, B., Bleuzen, P., Bataille, V., Squiban, P., Burg, G. and Urosevic, M.,  Adenovirus-mediated intralesional interferon-{gamma} gene transfer induces tumor regressions in cutaneous lymphomas,  Blood  2004. 
34. Fujii, Y., Kawakami, S., Okada, Y., Kageyama, Y. and Kihara, K.,  Regulation of prostate-specific antigen by activin A in prostate cancer LNCaP cells,  Am J Physiol Endocrinol Metab  286,  E927-31, 2004. 
35. Giese T., Zeier M., Meuer S.,  Analysis of NFAT-regulated gene expression in vivo: a novel perspective for optimal individualized doses of calcineurin inhibitors,  Nephrol Dial Transplant.  Suppl.4,  IV55-IV60, 2004. 
36. Koninger J, Giese NA, di Mola FF, Berberat P, Giese T, Esposito I, Bachem MG, Buchler MW, Friess H.,  Overexpressed decorin in pancreatic cancer: potential tumor growth inhibition and attenuation of chemotherapeutic action. ,  Clin Cancer Res.  10 (14),  4776-83, 2004. 
37. Raftery MJ, Wieland D, Gronewald S, Kraus AA, Giese T, Schonrich G.,  Shaping phenotype, function, and survival of dendritic cells by cytomegalovirus-encoded IL-10. ,  J Immunology  173 (5),  3383-91, 2004. 
38. Koninger J, Giese T, di Mola FF, Wente MN, Esposito I, Bachem MG, Giese NA, Buchler MW, Friess H.,  Pancreatic tumor cells influence the composition of the extracellular matrix. ,  Biochem Biophys Res Commun.  322 (3),  943-9, 2004. 
39. Schoels M, Dengler TJ, Richter R, Meuer SC, Giese T.,  Detection of cardiac allograft rejection by real-time PCR analysis of circulating mononuclear cells. ,  Clin Transplant.  18 (5),  513-7, 2004. 
40. Kayed H, Kleeff J, Ding J, Hammer J, Giese T, Zentgraf H, Buchler MW, Friess H.,  Expression analysis of MAC30 in human pancreatic cancer and tumors of the gastrointestinal tract. ,  Histol Histopathol.  19 (4),  1021-31, 2004. 
41. Hartel M, Di Mola FF, Gardini A, Zimmermann A, Di Sebastiano P, Guweidhi A, Innocenti P, Giese T, Giese N, Buchler MW, Friess H.,  Desmoplastic reaction influences pancreatic cancer growth behavior. ,  World J Surg.  28 (8),  818-25, 2004. 
42. Giese T, McGrath MS, Stumm S, Schempp H, Elstner E, Meuer SC.,  Differential effects on innate versus adaptive immune responses by WF10. ,  Cell Immunol.  229 (2),  149-58, 2004. 
43. Berberat, P.O., Z. Dambrauskas, A. Gulbinas, T. Giese, N. Giese, B. Kunzli, F. Autschbach, S. Meuer, M.W. Buchler, and H. Friess,  Inhibition of heme oxygenase-1 increases responsiveness of pancreatic cancer cells to anticancer treatment,  Clin Cancer Res.  11,  3790-3798, 2005. 
44. Schmidt, C., T. Giese, B. Ludwig, I. Mueller-Molaian, T. Marth, S. Zeuzem, S.C. Meuer, and A. Stallmach,  Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease,  Inflamm Bowel Dis.  11,  16-23, 2005. 
48. Li, J., J. Kleeff, I. Abiatari, H. Kayed, N.A. Giese, K. Felix, T. Giese, M.W. Buchler, and H. Friess,  Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer,  Mol Cancer.  4,  14, 2005. 
49. Berkeredjian-Ding, I.B., M. Wagner, V. Hornung, T. Giese, M. Schnurr, S. Endres, and G. Hartmann,  Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN,  J Immunology  174,  4043-4050, 2005. 
50. Kayed, H., J. Kleeff, I. Esposito, T. Giese, S. Keleg, N. Giese, M.W. Buchler, and H. Friess.,  Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas,  Mol Carcinog.  42,  183-192, 2005. 
51. Jahrsdorfer, B., L. Muhlenhoff, S.E. Blackwell, M. Wagner, H. Poeck, E. Hartmann, R. Jox, T. Giese, B. Emmerich, S. Endres, G.J. Weiner, and G. Hartmann,  B-cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotides.,  Clin Cancer Res.  11,  1490-1499, 2005. 
52. Giese, T., M. Engstner, U. Mansmann, W. Hartschuh, and B. Arden,  Quantification of melanoma micrometastases in sentinel lymph nodes using real-time RT-PCR,  J Invest Dermatol.  124,  633-637, 2005. 
53. Raykov, Z., L. Savelyeva, G. Balboni, T. Giese, J. Rommelaere, and N.A. Giese,  B1 lymphocytes and myeloid dendritic cells in lymphoid organs are preferential extratumoral sites of parvovirus minute virus of mice prototype strain expression,  J Virol.  79,  3517-3524, 2005. 
54. Jungling, B., I. Kindermann, C. Moser, W. Puschel, K.W. Ecker, H.J. Schafers, M. Bohm, S. Zeuzem, T. Giese, and A. Stallmach,  Development of ulcerative colitis after heart transplantation during immunosuppressive therapy,  Z Gastroenterol.  43,  195-199, 2005. 
55. Bachmeier BE, Vene R, Iancu CM, Pfeffer U, Mayer B, Noonan D, Albini A, Jochum M, Nerlich AG,  Transcriptional control of cell density dependent regulation of matrix metalloproteinase and TIMP expression in breast cancer cell lines.,  Thromb Haemost.  93(4),  761-9, 2005. 
56. Bachmeier BE, Albini A, Vene R, Benelli R, Noonan D, Weigert C, Weiler C, Lichtinghagen R, Jochum M, Nerlich AG.,  Cell density-dependent regulation of matrix metalloproteinase and TIMP expression in differently tumorigenic breast cancer cell lines,  Exp Cell Res.  305(1),  83-98, 2005. 
57. Wang XT, Sienel W, Eggeling S, Ludwig C, Stoelben E, Mueller J, Klein CA, Passlick B.,  Detection of disseminated tumor cells in mediastinoscopic lymph node biopsies and lymphadenectomy specimens of patients with NSCLC by quantitative RT-PCR,  Eur J Cardiothorac Surg.  Jul;28(1),  26-32, 2005. 
58. Farina, C., M. Krumbholz, T. Giese, G. Hartmann, F. Aloisi, and E. Meinl,  Preferential expression and function of Toll-like receptor 3 in human astrocytes,  J Neuroimmunol  159,  12-19, 2005. 
59. Dumortier, J., K. Schonig, H. Oberwinkler, R. Low, T. Giese, H. Bujard, P. Schirmacher, and U. Protzer,  Liver-specific expression of interferon gamma following adenoviral gene transfer controls hepatitis B virus replication in mice,  Gene Ther.  12,  668-677, 2005. 
60. Sido, B., T. Giese, F. Autschbach, F. Lasitschka, J. Braunstein, and S.C. Meuer,  Potential role of thioredoxin in immune responses in intestinal lamina propria T lymphocytes,  Eur J Immunol.  35,  408-417, 2005. 
61. Beyer, M. Kochanek, M. Giese, T. Endl, E. Weihrauch, M. R. Knolle, P. A. Classen, S. Schultze, J. L.,  In vivo peripheral expansion of naive CD4+CD25high FOXP3+ regulatory T cells in patients with multiple myeloma,  Blood  2006. 
62. Koninger, J. Giese, N. A. Bartel, M. di Mola, F. F. Berberat, P. O. di Sebastiano, P. Giese, T. Buchler, M. W. Friess, H.,  The ECM proteoglycan decorin links desmoplasia and inflammation in chronic pancreatitis,  J Clin Pathol  59,  21-7, 2006. 
63. Gulbinas, A. Berberat, P. O. Dambrauskas, Z. Giese, T. Giese, N. Autschbach, F. Kleeff, J. Meuer, S. Buchler, M. W. Friess, H.,  Aberrant gata-3 expression in human pancreatic cancer,  J Histochem Cytochem  54,  161-9, 2006. 
64. Kayed, H. Kleeff, J. Kolb, A. Ketterer, K. Keleg, S. Felix, K. Giese, T. Penzel, R. Zentgraf, H. Buchler, M. W. Korc, M. Friess, H.,  FXYD3 is overexpressed in pancreatic ductal adenocarcinoma and influences pancreatic cancer cell growth,  Int J Cancer  118,  43-54, 2006. 
65. Gu X, Lundqvist EN, Coates PJ, Thurfjell N, Wettersand E, Nylander K.,  Dysregulation of TAp63 mRNA and protein levels in psoriasis,  J Invest Dermatol.  126,  137-41, 2006. 


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